Abstract The fatal motor neuron (MN) disease Amyotrophic Lateral Sclerosis (ALS) is characterized by progressive MN degeneration.Phrenic MNs (phMNs) controlling the activity of the diaphragm are prone to degeneration in ALS, leading to death by respiratory failure.Understanding of the mechanisms of phMN degeneration in ALS is limited, mainly becaus
Proteotranscriptomic Analysis and Toxicity Assay Suggest the Functional Distinction between Venom Gland Chambers in Twin-Spotted Assassin Bug, Platymeris biguttatus
High Temperature Oil Assassin bugs use their salivary venoms for various purposes, including defense, prey paralyzation, and extra-oral digestion, but the mechanisms underlying the functional complexity of the venom remain largely unclear.Since venom glands are composed of several chambers, it is suggested that individual chambers may be specialize
Dental Implants in Patients with Oral Lichen Planus: A Systematic Review
Background and Objectives: To integrate the available published data on patients with oral lichen planus (OLP) rehabilitated with dental implants, as well as to review the recommendations for OLP patients receiving implants.Materials and Methods: An electronic search was undertaken in February 2019 using five databases.Publications reporting cases
Yessotoxin, a Marine Toxin, Exhibits Anti-Allergic and Anti-Tumoural Activities Inhibiting Melanoma Tumour Growth in a Preclinical Model.
Yessotoxins (YTXs) are a group of marine toxins produced by the dinoflagellates Protoceratium reticulatum, Lingulodinium polyedrum and Gonyaulax spinifera.They may have medical interest due to their potential role as anti-allergic but also anti-cancer compounds.However, their biological activities remain poorly characterized.Here, we show that the